Physostigma venenosum

Weakness; muscles won't respond or draw into knots; < cold. Weakness in lower limbs; coming from a spot between hips. Cramp in left calf at night in bed. Shuddering, < every draft. Horror of cold water. Averse to bathing. .................... Active mind, even during sleep. Floating sensation. Nothing seems right. Brain falls to side lain on. Pains from forehead down nose. Sensation as of a tight cap on head. Vertigo; stumbles on ascending or descending steps. Sensation as of a band about head. Twitching of eye muscles or of nose. Can't bear to raise eyelids. Accommodation affected. Seems to have swallowed a lump. Torpid bowels. Numb womb. Flushes of heat, < in palms. Sore bloated, red navel; hypogastrium, < standing. Tremor; in head, eyes, vision, nose, teeth, muscles, etc. Dartings, here and there. Tense eye-lids, can't open or close them. Blood-shot eyes. Creeping numbness from occiput down spine. Licks lips. Teeth feel rough. Tongue feels oily; scalded. Loose skin feeling in roof of mouth. Thick, leathery saliva. Hic-cough with short breath. Gripe in right hypochondrium. Groins pain alternately. Abdomen, > extending legs. Numbness at womb. Offensive odor from hands. Sweat in excitement. Heart seems to flutter in throat or over body. Sensitive spine. Jerking limbs. Shudders from every draft of air. Attacks of overpowering sleepiness, with feeling as if to lose consciousness.

Change of temperature. Eyestrain. Injury. Bathing. Heat and cold. Descending. Motion.

Lying with head low (Ver-v.). Exerting the will.

Spinal motor nerves. Eyes. Muscles. Left side.

Related: Agar. Gel. Nux-v.

Physostigma

Calabar Bean. Leguminosce.

Uncommon mental activity; cannot stop thinking. Vision dim; from blur or film; objects mixed.

Pain after using eyes; floating black spots, flashes of light, twitching of lids and muscles of eyes (Agar.) ; nistagmus.

Great prostration of muscular system ; impaired locomotion (Gels.).

Tremors or trembling of young persons from mental or physical disturbances.

PH YSOSTIGM A— ( Cmtmued) .

Idiopathic or traumatic tetanus; brought on or < by slightest breath of air from a person passing (Hyper., Lys., Nux, Strych.).

Hyper., Strych.

Calabar Bean This remedy and its active principle, Eserine, form a valuable addition to Materia Medica. Stimulates heart, raises blood pressure, and increases peristalsis. Causes contraction of the pupil and of the ciliary muscles. Induces a condition of short- sightedness. Spinal irritation, loss of motility, prostration, with very sensitive

vertebræ Fibrillary tremors. Rigidity of muscles; paralysis. Depresses the motor and reflex activity of the cord and causes loss of sensibility to pain, muscular weakness, followed by complete paralysis, although muscular contractility is not impaired. Paralysis and tremors, chorea. Meningeal irritation, with rigidity of muscles. Tetanus and trismus. Polymyelitis anterior. Eserine is used locally to produce contraction of pupil.

Constant pain on top; vertigo, with constrictive feeling of head. Pain over orbits; cannot bear to raise eyelids. Cerebro-spinal meningitis; general tetanic rigidity. Spastic conditions of the face-muscles.

Night-blindness (Opposite: Bothrops); photophobia; contraction of pupils; twitching of ocular muscles. Lagophthalmus. Muscæ volitantes; flashes of light; partial blindness. Glaucoma; paresis of accommodation; astigmatism. Profuse lachrymation. Spasm of ciliary muscles, with irritability after using eyes. Increasing myopia. Post-diphtheritic paralysis of eye and accommodation muscles.

Fluent coryza; burning and tingling of nostrils; nose stuffed and hot. Fever-blisters around nostrils.

Tongue feels sore on tip. Feeling as if a ball came up throat.

Strong heart-pulsation felt in throat.

Great pain immediately after eating. Sensitive to pressure in epigastric region. Pain extends into chest and down arms. Gastralgia; chronic constipation.

Irregular menstruation, with palpitation. Congestion of eyes. Rigid muscles.

Feeble pulse; palpitation; spasmodic action, with feeling pulsation through the whole body. Beats of heart distinctly perceptible in chest and head. Fluttering of heart felt in throat. Fatty degeneration (Cup ac).

Pain in right popliteal space. Burning and tingling in spine. Hands and feet numb. Sudden jerking of limbs on going to sleep. Tetanic convulsions. Locomotor ataxia. Numbness in paralyzed parts, crampy pains in limbs.

Compare: Eserine-the alkaloid of Physostigma––(slows action of heart and increases arterial tension; in ciliary spasm and spasmodic astigmatism due to irregular action of ciliary muscles; blepharo-spasms; pupils contracted. Twitching of lids, soreness of eyeballs, blurring of vision after using eyes, pains around eyes and head). Used locally to contract the pupil. Eserine contracts the pupils dilated by Atropin, but not those dilated by Gelsemium. Internally 6x. Eserin Salicylate (post-operative intestinal paralysis; meteorism. Hypodermically 1/60-1/40 gr). Compare also: Muscarin; Conium; Curare; Gels; Thebainum (tetanus); Piperazinum––(Uric acid conditions. Pruritus. Gout and urinary calculi. Constant

backache. Skin dry, urine scanty. Rheumatic urthritis. Give one grain daily in carbonated water. First and second decimal trituration three times a day). Antidote: Atropia. In full medicinal doses will relieve most of the effects of physostigmine.

Third potency. The neutral sulphate of Eserine is instilled into the eye, from one-half to four grains to one ounce distilled water, to induce contraction of pupil, in mydriasis, injuries to the eye, iritis, corneal ulcers, etc.