Proving Medicines
Organon Aphorism §113
The only exceptions to this are the narcotic medicines. As they, in their primary action, take away sometimes the sensibility and sensation, sometimes the irritability, it frequently happens that in their secondary action, even from moderate experimental doses on healthy bodies, an increased sensibility (and a greater irritability) is observable.
Samuel Hahnemann, Organon of Medicine, 6th edition, translated by William Boericke (1922, public domain). Checked word for word against the 1922 printing in October 2026.
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