Dose & Repetition of the Remedy

Organon Aphorism §253

Among the signs that, in all diseases, especially in such as are of an acute nature, inform us of a slight commencement of amelioration or aggravation that is not perceptible to every one, the state of mind and the whole demeanor of the patient are the most certain and instructive. In the case of ever so slight an improvement we observe a greater degree of comfort, increased calmness and freedom of the mind, higher spirits – a kind of return of the natural state. In the case of ever so small a commencement of aggravation we have, on the contrary, the exact opposite of this: a constrained helpless, pitiable state of the disposition, of the mind, of the whole demeanor, and of all gestures, postures and actions, which may be easily perceived on close observation, but cannot be described in words.

Samuel Hahnemann, Organon of Medicine, 6th edition, translated by William Boericke (1922, public domain). Checked word for word against the 1922 printing in October 2026.

Study notes for this aphorism are not published yet. They appear here once a homeopath has reviewed them.